The First Dose Missions are part of the Los Santos Drug Wars update, released in December 2022. They are a set of six missions that serve as the introduction to the Acid Lab, a new passive business. Players work with Dax and the Fooliganz to disrupt rival gangs and set up their own drug operation. The missions can be played solo or with up to three other players, and they are available from the Jobs menu or by calling Dax after meeting him in Freemode.
Each mission has a recommended level and can be completed on Normal or Hard difficulty. Hard mode offers higher payouts and is unlocked after completing the mission once. The missions involve tasks like stealing supplies, destroying enemy vehicles, and defending locations. Upon completing all six missions, players unlock the Acid Lab business, which generates passive income from producing and selling acid.
Payouts for each mission vary based on difficulty and time taken. On Hard difficulty, players can earn around $30,000-$50,000 per mission, plus bonuses for first-time completion. The total payout for all missions is approximately $200,000-$300,000, but these numbers may change with game updates. The Acid Lab itself requires an initial investment of $750,000 to set up, but it can become a profitable passive income source with upgrades. Note that prices and payouts are subject to change with updates; always check in-game for current values.


