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GTA Online

First Dose Missions

The First Dose Missions are a series of six story-driven contact missions in GTA Online that introduce the Acid Lab business and the Fooliganz crew.

Video via GTA Series Videos

Key facts

CostAcid Lab setup: $750,000 (after completing missions)
EarningsApprox $200,000-$300,000 total for all missions on Hard (check in-game for current rates)
Number of Missions6
UnlocksAcid Lab business
Difficulty OptionsNormal and Hard
Players1-4 (soloable)
First-Time Bonus2x GTA$ and RP on first completion of each mission (limited time events may apply)
Required LevelNone (available from rank 1)

The First Dose Missions are part of the Los Santos Drug Wars update, released in December 2022. They are a set of six missions that serve as the introduction to the Acid Lab, a new passive business. Players work with Dax and the Fooliganz to disrupt rival gangs and set up their own drug operation. The missions can be played solo or with up to three other players, and they are available from the Jobs menu or by calling Dax after meeting him in Freemode.

Each mission has a recommended level and can be completed on Normal or Hard difficulty. Hard mode offers higher payouts and is unlocked after completing the mission once. The missions involve tasks like stealing supplies, destroying enemy vehicles, and defending locations. Upon completing all six missions, players unlock the Acid Lab business, which generates passive income from producing and selling acid.

Payouts for each mission vary based on difficulty and time taken. On Hard difficulty, players can earn around $30,000-$50,000 per mission, plus bonuses for first-time completion. The total payout for all missions is approximately $200,000-$300,000, but these numbers may change with game updates. The Acid Lab itself requires an initial investment of $750,000 to set up, but it can become a profitable passive income source with upgrades. Note that prices and payouts are subject to change with updates; always check in-game for current values.

Tips

  • Play on Hard difficulty for higher payouts; you can replay missions from the pause menu.
  • Use an armored vehicle like the Kuruma for missions with heavy enemy fire.
  • In mission 'Welcome to the Troupe', destroy the acid lab equipment carefully to avoid failing the objective.
  • Complete all six missions to unlock the Acid Lab, then invest in equipment upgrades for better production.
  • Call Dax to start missions quickly; he can also be used to request the Acid Lab resupply later.
  • If playing solo, use snacks and armor from the interaction menu to survive longer.

FAQ

Can I replay the First Dose Missions?
Yes, you can replay them from the Jobs menu under Missions > Rockstar Created > First Dose, or by calling Dax.
Do I need to own a property to start these missions?
No, you just need to meet Dax in Freemode. He will appear near the Sandy Shores area after a certain point.
What is the best vehicle for these missions?
The Armored Kuruma is highly recommended due to its bullet resistance. Alternatively, the Duke O'Death is also good and free for returning players.

Video source: GTA Series Videos

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